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Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.
S Horn, E Endl, B Fehse, M M Weck, G W Mayr, M J├╝cker
Leukemia 2004; 18(11):1839-1849
ICID: 843090
IC™ Value: 14.69
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