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The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
Piotr Popik, Emmanuel Kostakis, Martyna Krawczyk, Gabriel Nowak, Bernadeta Szewczyk, Philip Krieter, Zhengming Chen, Shelley J Russek, Terrell T Gibbs, David H Farb, Phil Skolnick, Arnold S Lippa, Anthony S Basile
J Pharmacol Exp Ther 2006; 319(3):1244-1252
ICID: 696856
IC™ Value: 14.10
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