Sign in
Register
IC Journals Master List
IC Conferences
IC Journals Master List 2011
Submission Menu
Archives
|
IndexCopernicus Journal Abstract
| |
| EFFECT OF PH ON THE PHOTOSTABILITY OF SULPHACETAMIDE EYE-DROP SOLUTIONS [ EFFECT OF PH ON THE PHOTOSTABILITY OF SULPHACETAMIDE EYE-DROP SOLUTIONS ] TAUQIR AHMED, IQBAL AHMAD Pak. Jour. of Pharm. Sci 1988; 1(1):1-4 ICID: 900957 |
| Article type: Original article |
| IC™ Value: 3.00 |
| The photolysis of aqueous solutions of sulphacetamide and sulphanilamide has been studied at pH 3-11. The rate of phatolysis appears to be the highest around pH 5.0 and 3.0 for sulphace¬tamide and sulphanilamide respectively. The log k-pH profiles of both compounds in the buffered and unbuffered solutions are presented. Various buffer ions e.g. citrate and phosphate catalyase the photodegradation reactions. Sulphacetamide eye-drop solutions prepared at pH 7 to 9 have ideal stability and clinical efficacy |
: The photolysis of aqueous solutions of sulphacetamide and sulphanilamide has been studied at pH 3-11. The rate of phatolysis appears to be the highest around pH 5.0 and 3.0 for sulphace¬tamide and sulphanilamide respectively. The log k-pH profiles of both compounds in the buffered and unbuffered solutions are presented. Various buffer ions e.g. citrate and phosphate catalyase the photodegradation reactions. Sulphacetamide eye-drop solutions prepared at pH 7 to 9 have ideal stability and clinical efficacy |
 |
ICID 900957 |
Related articles |
|
|
|